Selected publications

Prereview journals 

  • Fuad Fares, Soliman Khatib, Jacob Vaya, Lital Sharvit, Einav Eizenberg, Solomon Wasser. Striatal Isolated from Cyathus Striatus Extracts Induces Apoptosis in Human Pancreatic Cancer Cells. Molecules. 2022, 27, 2746. https://doi.org/10.3390/molecules27092746
  • Sheelu Monga, Basem Fares, Rami Yashaev, Dov Melamed, Meygal Kahana, Fuad Fares, Abraham Weizman, Moshe Gavish. The effect of natural based formulation (NBF) on the respons of 7 macrophages to LPS as an in vitro model of inflammation. Journal of Fungi. 2022, 8, 321. https://doi.org/10.3390/jof8030321
  • Reem Miari, Naiel Azzam, Rinat Bar-Shalom, Fusd Fares. 5-aza-2’-deoxycytidine induces apoptosis and inhibits tumour growth in vivo of FaDu cells, a specific HPVnegative HNSCC cell line. PLOSE ONE, 2021, 16:e0253756
  • Lital Sharvit, Rinat Bar-Shalom, Naiel Azzam, Yaniv Yechiel, Solomon Wasser, Fuad Fares. Cyathus striatus Extract Induces Apoptosis in Human Pancreatic Cancer Cells and Inhibits Xenograft Tumor Growth In Vivo. Cancers. 2021, 13,2017. https://doi.org/10.3390/cancers13092017
  • Naiel Azzam, Rinat Bar-Shalom, Fusd Fares. A novel follitopin analog inhibits follitropin activity in vitro. Pharmaceutics, 13, 325,
  • Xiao Gao, Qingwei Wang4, Ying Wang, Jiang Liu, Shuang Liu, Jian Liu, Xingli Zhou, Li Zhou, Hui Chen, Linian Pan, Jiwei Chen, Da Wang, Qing Zhang, Shihui Shen, Yu Xiao, Zhipeng Wu, Yiyun Cheng, Geng Chen, Jun Qin, Lan Huang, Pei Zhang, Chuangui Wang, Robb E. Moses, David M. Lonard, Bert W. O’Malley, Fuad Fares, Bianhong Zhang, Xiaotao Li, Lei Li , Jianru Xiao.The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells. Nature Communications. 2020; 11: 3904. Published online 2020 Aug 6. doi: 10.1038/s41467-020-17667-7
  • Rinat Bar-Shalom, Naiel Azzam, Lital Sharvit, Margalit Bergman, Shlomo Graossman, and Fuad Fares. Inula Viscosa extract inhibits growth of colorectal cancer cells in vitro and in vivo through induction of apoptosis. Frontiers in Oncology- Pharmacology of Anti-Cancer Drugs. 9:227, doi:10.3389/fonc.2019.00227. eCollection
  • Fuad Fares, Naiel Azzam. : Development of long-acting recombinant glycoprotein hormones by increasing the carbohydrate content. Drug Discovery Today  pii: S1359-6446,
  • Marisa Friederich, Sharita Timal, Christopher Powell, Cristina Dallabona, Alina Kurolap, Sara Palacios-Zambrano, Drago Bratkovic, Terry Derks, David Bick, Katelijne Bouman, Kathryn Chatfield, #Nadine Damouny-Naoum, Megan Dishop, Tzipora Falik-Zaccai, Fuad Fares, Ayalla Fedida, Ileana Ferrero, Renata Gallagher, Rafael Garesse, Micol Gilberti, Cristina González, Katherine Gowan, Claire Habib, Rebecca Halligan, Limor Kalfon, Kaz Knight, Dirk J Lefeber, Laura Mamblona, Hanna Mandel, Adi Mory, John Ottoson, Tamar Paperna, Ger Pruijn, Pedro Rebelo-Guiomar, Ann Saada, Bruno Sainz Jr., Hayley Salvemini, Mirthe Schoots, Jan Smeitink, Maciej Szukszto, Hendrik Ter Horst, Frans van den Brandt, FrancJan van Spronsen, Joris Veltman, Eric Wartchow, Liesbeth Wintjes, Yaniv Zohar, Miguel Fernandez-Moreno, Hagit Baris, Claudia Donnini, Michal Minczuk, Richard Rodenburg, and Johan Van Hove. Pathogenic variants in glutamyl-tRNA(Gln) amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nature Communications 9:4065, DOI: 10.1038/s41467-018-06250-w
  • Tameemi Abdalla-Moady, Amir Peleg, Orit Sadeh, Khader Badarneh and Fuad Fares. Whole-exome sequencing identifies a novel homozygous frameshift mutation in the MTMR2 gene as a causative mutation in a patient with Charcot-Marie-Tooth disease type 4B1. Molecular Neurobiology. 55(4):3546-3550,
  • Naiel Azzam, Rinat Bar-Shalom, Anwar Saab and Fuad Fares. Germline Polymorphisms on RET Proto-oncogene involved in Medullary Thyroid Carcinoma in a Druze Family –A case study. European Journal of Cancer. 82:149-152,
  • Fuad Fares. The anti-carcinogenic effect of indole-3-carbinol and 3,3′- diindolylmethane and their mechanism of action. Open-access article, Medicinal Chemistry (Special issue: Cancer Prevention and therapy). doi: 10.4172/2161-0444.S1-002, 2014 [www.omicsonline.org] (Invited Review).
  • Tina Napso and Fuad Fares. Zebularine Induces Prolonged Apoptosis Effect in Squamous Cell Carcinoma through the Intrinsic Pathway. Inter Journal of Oncology. 44:1971-1979,
  • Fuad Fares, Naeil Azzam, Basem Fares, Stig Larsen, Steen Lindkaer-Jensen. Benzene-Poly-Carboxylic Acid Complex, a novel anti-cancer agent induces apoptosis in human breast cancer cells. PLoS ONE, 9:e85156 (1-8),

Patents 

  • Fuad Fares, Lital Sharvit, Solomon P Wasser. Novel Cyathus Striatus mushroom strain, extracts thereof and pharmaceutical compositions comprising them
  • Fuad Fares, Lital Sharvit, Solomon P Wasser. Composition and method for treating cancer.
  • Fuad Fares, Reem Miari. Human head and neck cancer treatment.
  • Fuad Fares, Rinat Bar-Shalom, Shlomo Grossman, Margalit Bergman. Inula Viscosae fraction can be used for prevention of tumor formation and cancer treatment.
  • Fuad Fares and Eyal Fima. Long-acting polypeptides and methods of producing same
  • Fuad Fares and Eyal Fima. Long-acting growth hormone and methods of producing same
  • Fuad Fares and Eyal Fima. Long-acting EPO polypeptides and derivatives thereof and methods thereof