Research Interest

• Structure-Function of glycoprotein hormones using site-directed mutagenesis and gene transfer. These studies led us to the development of a novel strategy for developing long acting recombinant proteins that used in clinics; ELONVA (long-acting FSH is used in treatment of infertility and IVF), Somatrogon, (long-acting human growth hormone) and Long-acting erythropoietin. Base on this technology I found a start up company for “designing long-acting recombinant proteins”, PROLOR Biotechnology. Moreover, using these techniques we succeeded to develop antagonists for FSH and TSH.
• Identifying apoptotic factors and understanding their molecular mechanism of action. Based on the results of our laboratory, I am the founder of CanCurX, a start-up company at University of Haifa for developing new strategies for treatment of cancer.
• Identifying gene alterations that responsible for development of human genetic diseases and familial cancer